Skip to main content
. 2021 Nov 26;9(11):e26065. doi: 10.2196/26065

Table 5.

Claim category and explanations of claim categories extracted manually from all noncredible sentences from the cholesterol and statins topic.

Claim category Claim explanation
(stat) Side effects Statins’ side effects outweigh the benefits
(chol) Not an indicator of CVDa risk Total cholesterol is not an indicator of CVD
Diet as good as drugs Aggregation of different dietary interventions to lower cholesterol, triglycerides, or sugars
(chol) Too low is harmful Too low cholesterol level is harmful
Lifestyle changes are enough People can lower cholesterol level just by developing good habits and eating a proper diet
Big pharma People (eg, physicians and pharmaceutical company workers) make considerable profit through prescribing statins
Inflammation theory It is inflammation that causes CVD, not excessive cholesterol level; cholesterol is an effect, not a cause
(stat) Cause diabetes Statins increase the risk of diabetes
(stat) Not needed Statins are given to healthy people who do not need them
(chol) Makes cells and protects nerves Cholesterol produces hormones that make body cells and protect nerves
(stat) Not effective Statins do not fulfill their role in reducing the risk of CVD
(stat) Prescription based solely on (chol) level Statin prescription is based solely on total cholesterol level
Detailed data Sentences contain detailed data, for example, “LDLb cholesterol level should not exceed 200 md/dL”
(stat) Cause cognitive impairment Statin consumption causes different forms of cognitive impairment (including memory loss and slow information processing)
(stat) Not studied enough Statins’ effectiveness is not studied enough
High HDLc neutralizes high LDL HDL is a so-called good cholesterol, whereas LDL is a so-called bad cholesterol; high levels of the former neutralize negative consequences of high levels of the latter
Harmful CoQ10d loss Statin-related CoQ10 loss is harmful
(chol) Consumption not an issue People should not worry about cholesterol consumption
Lifestyle versus statins Lifestyle changes are more effective ways to prevent CVDs than statin consumption
No liver function monitoring Monitoring of liver function tests is no longer recommended in patients on statin therapy
Miscellaneous None of the above

aCVD: cardiovascular disease.

bLDL: low-density lipoprotein.

cHDL: high-density lipoprotein.

dCoQ10: Coenzyme Q10.