TABLE 1.
Patient characteristics
| All (%) | Without adjuvant therapy (N = 75) (percentage of 75 patients) | With adjuvant therapy (N = 168) (percentage of 168 patients) | P value | |
|---|---|---|---|---|
| Age (years old), median (range) | 50 (27‐85) | 52 (27‐85) | 49 (31‐72) | .413 |
| Gender | ||||
| Male | 214 (88.1) | 67 (89.3) | 147 (87.5) | .684 |
| Female | 29 (11.9) | 8 (10.7) | 21 (12.5) | |
| Primary site | ||||
| Buccal | 101 (41.6) | 38 (50.7) | 63 (37.5) | .000 |
| Tongue | 90 (37) | 17 (22.7) | 73 (43.5) | |
| Mouth floor | 10 (4.1) | 5 (6.6) | 5 (3.0) | |
| Retromolar trigone | 10 (4.1) | 4 (5.3) | 6 (3.6) | |
| Gingiva | 24 (9.9) | 4 (5.3) | 20 (11.9) | |
| Lip | 5 (2.1) | 4 (5.3) | 1 (0.6) | |
| Hard palate | 3 (1.2) | 3 (4.0) | 0 | |
| Differentiation | ||||
| Well | 64 (26.3) | 22 (29.3) | 42 (25) | .262 |
| Moderate | 155 (63.8) | 49 (65.3) | 106 (63.1) | |
| Poor | 24 (9.9) | 4 (5.3) | 20 (11.9) | |
| pT | ||||
| T1 | 17 (7.0) | 9 (12.0) | 8 (4.8) | .000 |
| T2 | 83 (34.2) | 43 (57.3) | 40 (23.8) | |
| T3 | 86 (35.3) | 14 (18.7) | 72 (42.9) | |
| T4a | 51 (21) | 9 (12.0) | 42 (25.0) | |
| T4b | 6 (2.5) | 0 | 6 (3.6) | |
| LVI | ||||
| Positive | 25 (10.3) | 7 (9.3) | 18 (10.7) | .743 |
| Negative | 218 (89.7) | 68 (80.7) | 150 (89.3) | |
| PNI | ||||
| Positive | 112 (46.1) | 22 (29.3) | 90 (53.6) | .000 |
| Negative | 131 (53.9) | 53 (70.7) | 78 (46.4) | |
| Margin | ||||
| Clear | 129 (53.1) | 46 (61.3) | 83 (49.4) | .085 |
| Close | 114 (46.9) | 29 (38.7) | 85 (50.6) |
Abbreviations: LVI, lymphovascular invasion; PNI, perineural invasion.