TABLE 2.
Five‐year (%) | OS | P value | LRFS | P value | RRFS | P value | DMFS | P value |
---|---|---|---|---|---|---|---|---|
Age (y) | ||||||||
<65 | 69.1 | .315 | 64.0 | .796 | 64.9 | .386 | 68.7 | .245 |
≥65 | 59.6 | 59.6 | 61.3 | 57.4 | ||||
Gender | ||||||||
Male | 68.5 | .498 | 63.8 | .580 | 64.5 | .575 | 67.8 | .573 |
Female | 66.1 | 63.9 | 64.2 | 66.4 | ||||
Primary site | ||||||||
Buccal | 69.6 | .329 | 63.2 | .277 | 65.5 | .390 | 68.8 | .344 |
Tongue | 61.6 | 56.9 | 57.1 | 60.9 | ||||
Mouth floor | 100 | 100 | 90.0 | 100 | ||||
Retromolar trigone | 80.0 | 80.0 | 80.0 | 80.0 | ||||
Gingiva | 70.8 | 70.8 | 70.8 | 70.8 | ||||
Lip | 50.0 | 50.0 | 60.0 | 50.0 | ||||
Hard palate | 66.7 | 66.7 | 66.7 | 66.7 | ||||
Differentiation | ||||||||
Well/moderate | 71.2 | .001 | 66.3 | .019 | 67.0 | .021 | 70.5 | .003 |
Poor | 40.9 | 40.9 | 40.9 | 41.3 | ||||
pT | ||||||||
T1/2 | 74.2 | .009 | 66.8 | .095 | 68.3 | .081 | 74.3 | .005 |
T3/4 | 63.8 | 61.4 | 61.7 | 62.7 | ||||
LVI | ||||||||
Positive | 68.5 | .741 | 53.8 | .109 | 53.6 | .118 | 68.5 | .816 |
Negative | 68.1 | 64.8 | 65.6 | 67.4 | ||||
PNI | ||||||||
Positive | 60.7 | .019 | 56.3 | .021 | 56.7 | .019 | 59.4 | .009 |
Negative | 74.6 | 70.2 | 71.2 | 74.6 | ||||
Margin | ||||||||
Clear | 69.5 | .293 | 65.5 | .231 | 65.8 | .323 | 68.9 | .271 |
Close | 66.4 | 61.4 | 62.7 | 65.9 | ||||
Adjuvant therapy | ||||||||
No | 72.1 | .253 | 65.9 | .671 | 64.7 | .869 | 72.1 | .175 |
Yes | 66.3 | 62.8 | 64.3 | 65.4 | ||||
Adjuvant therapy | ||||||||
No | 72.1 | .270 | 65.9 | .525 | 64.7 | .600 | 72.1 | .213 |
RT | 73.0 | 69.1 | 70.4 | 71.7 | ||||
CCRT | 60.5 | 57.2 | 58.9 | 59.8 |
Abbreviations: CCRT, concurrent chemoradiaiton; DMFS, distant metastasis‐free survival; LRFS, local recurrence‐free survival; LVI, lymphovascular invasion; OS, overall survival; PNI, perineural invasion; RRFS, regional recurrence‐free survival; RT, radiation therapy.