TABLE 3.
Multivariate analysis for survival in all single node patients
| Hazard ratio, 95% confidence interval | OS | P value | LRFS | P value | RRFS | P value | DMFS | P value |
|---|---|---|---|---|---|---|---|---|
| Differentiation | ||||||||
| Well/moderate | 1 | .002 | 1 | .020 | 1 | .018 | 1 | .004 |
| Poor | 2.575 (1.431‐4.635) | 1.995 (1.118‐3.561) | 2.020 (1.131‐3.610) | 2.387 (1.330‐4.286) | ||||
| pT | ||||||||
| T1/2 | 1 | .016 | 1 | .117 | 1 | .068 | 1 | .014 |
| T3/4 | 1.888 (1.127‐3.163) | 1.448 (0.911‐2.301) | 1.546 (0.969‐2.465) | 1.907 (1.142‐3.186) | ||||
| PNI | ||||||||
| Negative | 1 | .109 | 1 | .062 | 1 | .051 | 1 | .067 |
| Positive | 1.447 (0.921‐2.274) | 1.498 (0.980‐2.289) | 1.530 (0.999‐2.345) | 1.518 (0.971‐2.374) | ||||
| Adjuvant therapy | ||||||||
| No | 1 | .754 | 1 | .464 | 1 | .183 | 1 | .887 |
| Yes | 0.918 (0.537‐1.568) | 0.835 (0.515‐1.354) | 0.724 (0.450‐1.165) | 0.962 (0.565‐1.640) |
Abbreviations: DMFS, distant metastasis‐free survival; LRFS, local recurrence‐free survival; OS, overall survival; RRFS, regional recurrence‐free survival.