Table 3.
Cytokine levels of CD subjects stratified by ASAS MRI positivity
Variable | ASAS MRI positive (N = 6, 18%) |
ASAS MRI negative (N = 25, 82%) |
p-value |
---|---|---|---|
Cytokine | |||
Interleukin 2 | 4.7 ± 2.0 | 5.6 ± 7.8 | 0.79 |
Interleukin 4 | 3.5 ± 1.6 | 5.7 ± 4.6 | 0.33 |
Interleukin 5 | 3.7 ± 0.0 | 3.8 ± 0.1 | 0.25 |
Interleukin 6 | 6.2 ± 7.2 | 5.1 ± 6.9 | 0.71 |
Interleukin 9 | 2.4 ± 1.5 | 1.9 ± 0.9 | 0.29 |
Interleukin 10 | 31.0 ± 59.3 | 6.5 ± 1.8 | 0.36 |
Interleukin 13 | 8.9 ± 6.3 | 8.9 ± 4.4 | 0.93 |
Interleukin 12–23 | 214.0 ± 159.5 | 259.1 ± 227.7 | 0.65 |
Interleukin 17A | 25.3 ± 13.1 | 21.1 ± 10.5 | 0.40 |
Interleukin 17F | 4.8 ± 2.2 | 3.8 ± 3.5 | 0.49 |
Interleukin 21 | 19.8 ± 36.2 | 40.0 ± 43.2 | 0.30 |
Interleukin 22 | 15.2 ± 7.1 | 16.7 ± 11.2 | 0.75 |
Interferon-γ | 75.7 ± 31.0 | 79.0 ± 28.8 | 0.80 |
TNF-α | 19.5 ± 15.2 | 35.4 ± 94.1 | 0.68 |
ASAS=Assessment of SpondyloArthritis international Society, CD=Crohn’s disease, TNF= tumor necrosis factor