Table 3.
Serum metabolites associated with patella and tibia Pb
| Patella Pb | Tibia Pb | |||
|---|---|---|---|---|
| Compounda | Estimate (SE) | P | Estimate (SE) | P |
| Significant in patella and tibia | ||||
| 5-Aminopentanoic acid | -0.049 (0.015) | 1.82E-03 | -0.049 (0.022) | 2.46E-02 |
| L-Arginine | -0.010 (0.005) | 4.70E-02 | -0.015 (0.007) | 2.74E-02 |
| Significant in patella | ||||
| Betaine | 0.031 (0.009) | 5.31E-04*** | 0.018 (0.014) | 0.19 |
| Biliverdin | 0.017 (0.007) | 1.97E-02 | 0.007 (0.010) | 0.45 |
| Oxoproline | 0.012 (0.005) | 2.05E-02 | 0.004 (0.007) | 0.60 |
| Pyroglutamate | 0.012 (0.005) | 2.09E-02 | 0.004 (0.007) | 0.60 |
| 7-Methylguanine | -0.004 (0.002) | 3.29E-02 | -0.003 (0.003) | 0.34 |
| POV-PC | -0.018 (0.008) | 3.42E-02 | -0.022 (0.011) | 0.05 |
| Significant in tibia | ||||
| 1-Linoleoylglycerol | 0.016 (0.012) | 0.18 | 0.049 (0.015) | 1.50E-03* |
| Glycochenodeoxycholic acid | 0.009 (0.012) | 0.44 | 0.044 (0.016) | 6.83E-03 |
| Docosahexaenoic acid (DHA) | -0.009 (0.006) | 0.16 | -0.022 (0.008) | 9.21E-03 |
| Allantoin | -0.011 (0.007) | 0.13 | -0.026 (0.010) | 9.56E-03 |
| Glycocholic acid | 0.015 (0.011) | 0.18 | 0.037 (0.015) | 1.74E-02 |
| MEP (Mono-ethyl phthalate) | 0.025 (0.027) | 0.36 | 0.085 (0.037) | 2.32E-02 |
| Oleoyl-Glycerol | -0.011 (0.010) | 0.26 | -0.030 (0.013) | 2.79E-02 |
| 1-Arachidonoylglycerol | 0.006 (0.007) | 0.34 | 0.020 (0.009) | 2.89E-02 |
| L-Isoleucine | 0.007 (0.005) | 0.17 | 0.014 (0.007) | 3.66E-02 |
| Indole-3-Carboxylic acid | 0.004 (0.006) | 0.54 | -0.017 (0.008) | 3.82E-02 |
| Erucic acid | -0.006 (0.006) | 0.32 | -0.017 (0.008) | 3.96E-02 |
| 2-Undecanone | 0.008 (0.005) | 0.07 | 0.013 (0.006) | 4.10E-02 |
*Significant at thresholds of ENT75%, **ENT95%, and ***ENT99%; a.Metabolites were identified at MSI Level 1 confidence