Fig. 6.

One-pot UniNicE-seq of 25 cells compared with scATAC-seq in GM12878 cells. A Comparison of FRiP scores of one-pot UniNicE-seq 500 cells and scATAC-seq. B Genome-wide comparison of accessible chromatin between one-pot UniNicE-seq 500 and scATAC-seq using Pearson correlation. C Venn diagram showing common and unique accessible region peaks between one-pot UniNicE-seq 500 cells and scATAC-seq. D Genome-wide metagene plot of TSS (top panel) and enhancer elements (bottom panel) with ± 2 Kb of flanking region of one-pot UniNicE-seq 500 and scATAC-seq. E Peak annotation of one-pot UniNicE-seq 500 and scATAC-seq. F Representative IGV genomic tracks of the normalized read density of the one-pot UniNicE-seq 500 cells, 25 cells, ATAC-seq, Omni ATAC-seq and scATAC-seq. All scATAC-seq data used for this analysis was derived from 384 cumulative cell reads