Fig. 1.

The Chito-Code: fiction today, fact tomorrow? While chitosan-specific receptors for the perception of chitosan oligomers with defined patterns of acetylation (PA) acting as functional biologics triggering specific responses in target cells have not yet been described, and while the involvement of partially deacetylated domains with specific PAs within otherwise fully acetylated chitins in the protein-assisted assembly of functional biomaterials is fully hypothetical, regio-selective chitin deacetylases and sequence-dependent chitosan hydrolases and chitin-binding proteins are well known