TABLE 2.

Correlation between the miR‐503‐3p expression and clinicopathological factors in 55 patients with OSCC

		miR‐503‐3p expression
		High	Low
Characteristic	Total	n (%)	n (%)	p‐value
Age (years)
Median	67.2	66.7	67.5
Range	39‐85	39‐85	41‐85
≤ 65	21	11(52.3)	10(47.7)	0.864
> 65	34	17(50)	17(50)
Sex
Male	32	18(56.2)	14(43.8)	0.350
Female	23	10(43.5)	13(56.5)
Primary site
Tongue	16	8(50)	8(50)	0.881
Mandible	20	9(45)	11(55)
Maxilla	6	3(50)	3(50)
Oral floor	4	2(50)	2(50)
Buccal mucosa	9	6(66.7)	3(33.3)
T‐category
T2	18	8(44.4)	10(55.6)	0.800
T3, T4	37	20(54.1)	17(45.9)
N‐category
N0	23	8(34.8)	15(65.2)	0.043*
≥ N1	32	20(62.5)	12(37.5)
Differentiation
Well	43	22(51.1)	21(48.9)	0.943
Moderate, poor	12	6(50)	6(50)
Lymphovascular invasion
Yes	3	1(33.3)	2(66.7)	0.531
No	52	27(51.9)	25(48.1)
Extracapsular extension
Yes	5	3(60)	2(40)	0.899
No	27	17(62.3)	10(37.7)
Pathological response
Grade I, IIa (poor response)	12	8(66.7)	4(33.3)	0.003**
Grade IIb (partical response)	13	6(46.1)	7(53.9)
Grade ≥ III (complete response)	30	14(46.7)	16(53.3)
Recurrence
Yes	12	9(75)	3(25)	0.059
No	43	19(44.2)	24(55.8)

The chi‐square test was used to examine the relationships between miR‐503‐3p expression and clinicopathologic factors. *p < 0.05 and **p < 0.01.

Abbreviation: OSCC, oral squamous cell carcinoma.