TABLE 3.
Multivariate analysis of prognostic factors by the Cox proportional hazards regression models
| OS | DFS | ||||
|---|---|---|---|---|---|
| Variables | n | Hazard ratio (95% CI) | p‐value | Hazard ratio (95% CI) | p‐value |
| T‐category | |||||
| T3, T4 | 37 | 3.842 (1.202–17.289) | 0.021* | 3.145 (0.947–14.456) | 0.062 |
| T2 | 18 | ||||
| N‐category | |||||
| ≧ N1 | 32 | 1.334 (0.485–3.985) | 0.579 | 2.224 (0.735–8.204) | 0.161 |
| N0 | 23 | ||||
| Differentiation | |||||
| Moderate, poor | 12 | 3.121 (1.145–8.168) | 0.027* | 2.697 (0.916–7.501) | 2.697 |
| Well | 43 | ||||
| Lymphovascular invasion | |||||
| Yes | 3 | 0.248 (0.012–1.507) | 0.145 | 3.117 (0.496–61.798) | 0.254 |
| No | 52 | ||||
| Extracapsular extension | |||||
| Yes | 5 | 3.348 (0.819–11.647) | 0.088 | 2.685 (0.642–9.616) | 0.164 |
| No | 27 | ||||
| Pathological response | |||||
| Grade I, II | 25 | 2.907 (1.097–8.532) | 0.031* | 2.204 (0.774–6.739) | 0.138 |
| Grade ≧ III | 30 | ||||
| miR‐503‐3p expression | |||||
| High | 28 | 3.006 (1.086–9.207) | 0.033* | 2.803 (0.948–9.421) | 0.062 |
| Low | 27 | ||||