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. 2021 Jan 18;32(1-2):113–127. doi: 10.1089/hum.2020.127

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Copyright 2021, by Mary Ann Liebert, Inc., publishers

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Figure 3. — T lymphocyte reconstitution with cocal-LV vector injection. (A) Kinetics of gene marking in PB lymphocytes from dogs treated with cocal-LV (H983 and H985) and compared with FV vector (H864 and H867) based on fluorophore expression. Lymphocyte population was defined based on forward and side scatter. (B) Kinetics of CD3⁺ cell reconstitution (based on CD3⁺ cells per microliter of blood) in the same animals as described in (A). Normal range of lymphocyte counts is shown by horizontal dashed lines. (C) Kinetics of lymphocyte reconstitution (based on lymphocyte per microliter count) in the same animals as described in (A). Horizontal dashed lines show normal range of lymphocyte counts. LV, lentiviral vector.