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. 2016 Apr 14;2016(4):CD011491. doi: 10.1002/14651858.CD011491.pub2

Comparison 1. Prophylactic oxytocin injection (delivered by CHO) versus control (no injection).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Severe postpartum haemorrhage 1 (> 1000 mL) 1 1570 Risk Ratio (M‐H, Fixed, 95% CI) 0.16 [0.02, 1.30]
2 Severe maternal morbidity 1 1570 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3 Maternal deaths 1 1570 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4 Postpartum haemorrhage (1) > 500 mL1 1 1569 Risk Ratio (M‐H, Fixed, 95% CI) 0.48 [0.28, 0.81]
5 Postpartum haemorrhage (1) >500 mL (adjusted by design effect) 1 1174 Risk Ratio (M‐H, Fixed, 95% CI) 0.49 [0.27, 0.90]
6 Transfer or referral to a healthcare facility 1 1586 Risk Ratio (M‐H, Fixed, 95% CI) 0.72 [0.34, 1.56]
7 Maternal major/minor adverse events 1 1570 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
8 Oxytocin use during labour 1 1570 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
9 Stillbirth 1 2006 Risk Ratio (M‐H, Fixed, 95% CI) 1.27 [0.67, 2.40]
10 Early infant death (0‐3 days) 1 1969 Risk Ratio (M‐H, Fixed, 95% CI) 1.03 [0.35, 3.07]