Table 3.
Rate of rise and fall in coated-platelets after aSAH
| Clinical response | Days 0–4 |
Days 4–21 |
||||||
|---|---|---|---|---|---|---|---|---|
| Estimated rate of change (%/day) | 95% CI on rate of change (%/day) | P value | Estimated rate of change (%/day) | 95% CI on rate of change (%/day) | P value | |||
| DCI (n = 45) | ||||||||
| Yes | 4.6 | 2.8 | 6.5 | < 0.0001* | − 1.6 | − 1.8 | − 1.4 | < 0.0001* |
| No | − 2.0 | − 4.5 | 0.5 | − 0.6 | − 1.0 | − 0.2 | ||
| MOCA (n = 24) | ||||||||
| < 26 | 2.9 | − 0.2 | 5.9 | 0.499 | − 1.3 | − 1.7 | − 1.0 | 0.360 |
| ≥ 26 | 1.4 | − 1.8 | 4.5 | − 1.6 | − 2.1 | − 1.2 | ||
| mRS (n = 27) | ||||||||
| 3–6 | 3.4 | 0.0 | 6.0 | 0.298 | − 1.3 | − 1.6 | − 1.0 | 0.421 |
| 0–2 | 1.5 | − 1.0 | 4.0 | − 1.5 | − 1.8 | − 1.1 | ||
| Aneurysm securing procedure (n = 45) | ||||||||
| Clip | 2.5 | 0.9 | 4.2 | 0.753 | − 1.6 | − 1.8 | − 1.3 | 0.001* |
| Coil | 3.1 | − 0.3 | 6.6 | − 0.8 | − 1.2 | − 0.4 | ||
The asterisk indicates a significant difference between groups in the rate of change of coated-platelets before and after the transition day (at a significance level of 0.05)
aSAH aneurysmal subarachnoid hemorrhage, DCI delayed cerebral ischemia, MOCA Montreal cognitive assessment test, mRS modified Rankin scale