Fig. 2.
A 56-year-old woman with post-menopause uterus bleeding and mismatch repair deficient (dMMR) endometrioid endometrial adenocarcinoma (EEA), grade 3 with stage IA. MR images of: a T2WI; b APTw, with mean APTw value 3.0% by two readers; c DWI original map (b = 1000 s/mm2); d pseudo colored map of ADC, with mean ADC values 0.721 × 10−3 mm2/s by two readers. MMR immunohistochemistry analysis revealed the loss of nuclear staining in tumor cells for MLH1 (e) and PMS2 (f), respectively (×100 magnification); positive staining in stromal cells and normal endometrial glands serves as internal control. Loss of MSH2 (g) and MSH6 (h) expression, respectively (×100 magnification). Brown stain is positive staining and blue counterstain is indicative of absent or negative staining