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. 2021 Aug 19;22(12):3080–3088. doi: 10.1093/pm/pnab257

Table 1.

Participants’ characteristics by trajectories of days of overall medical cannabis use and days of high-THC medical cannabis use

Total Sample Clusters of Overall
Medical Cannabis Use
Clusters of High-THC
Medical Cannabis Use
N = 99 Infrequent Use (n=30) Occasional Use (n=28) Frequent Use (n=41) P Infrequent Use (n=50) Occasional Use (n=24) Frequent Use (n=25) P
Sociodemographic characteristics
 Age, years, mean±SD 53.1±13.5 53.4±14.6 51.4±13.5 54±12.8 0.72 55.3±13.3 50.5±15.8 51.2±10.8 0.16
 Female gender, n (%) 62 (62.6) 17 (56.7) 20 (71.4) 25 (61) 0.49 34 (68) 15 (62.5) 13 (52) 0.40
 Race/ethnicity, n (%) 0.004 0.03
  Non-Hispanic White 45 (45.5) 7 (23.3) 12 (42.9) 26 (63.4) 16 (32) 12 (50) 17 (68)
  Non-Hispanic Black 23 (23.2) 9 (30) 11 (39.3) 3 (7.3) 14 (28) 8 (33.3) 1 (4)
  Hispanic (any race) 25 (25.3) 12 (40) 4 (14.3) 9 (22) 16 (32) 3 (12.5) 6 (24)
  Non-Hispanic other race 6 (6.0) 2 (6.7) 1 (3.5) 3 (7.3) 4 (8) 1 (4.2) 1 (4)
 Currently employed, n (%) 22 (22.2) 3 (10) 11 (39.3) 8 (19.5) 0.02 12 (24) 5 (20.8) 5 (20) 0.91
 Health insurance, n (%)^ 0.098 0.73
  Public 72 (72.7) 26 (86.7) 19 (67.9) 27 (65.9) 38 (76) 16 (66.7) 18 (72)
  Private 26 (26.3) 3 (10) 9 (32.1) 14 (34.2) 11 (22) 8 (33.3) 7 (28)
Substance use, n (%)
 Current nonmedical cannabis use 40 (40.4) 14 (46.7) 12 (42.9) 14 (34.2) 0.54 18 (36) 11 (45.8) 11 (44) 0.66
 Cannabis dependence or abusea 8 (8.1) 2 (6.7) 1 (3.6) 5 (12.2) 0.41 2 (4) 3 (12.5) 3 (12) 0.32
 >7 days of opioid use in the past 14 days 40 (40.4) 14 (46.7) 6 (21.4) 20 (48.8) 0.053 21 (42) 10 (41.7) 9 (36) 0.87
 Problematic alcohol useb 6 (6.1) 1 (3.3) 3 (10.7) 2 (4.9) 0.46 2 (4) 2 (8.3) 2 (8) 0.69
 Current tobacco use 31 (31.3) 12 (40) 4 (14.3) 16 (36.6) 0.07 15 (30) 5 (20.8) 11 (44) 0.21
Pain and mental health
 PEG score,c mean±SD 7.3±2.0 7.6±2.2 7.6±1.5 6.9±2.1 0.20 7.3±2.2 7.4±1.7 7.3±1.9 0.92
 Moderate or severe anxiety symptoms,d n (%) 32 (32.3) 7 (23.3) 11 (39.3) 14 (34.2) 0.41 12 (24) 8 (33.3) 12 (48) 0.11
 Moderate or severe depression symptoms,e n (%) 42 (42.4) 15 (50) 12 (42.9) 15 (36.6) 0.53 20 (40) 9 (37.5) 13 (52) 0.52
 High PTSD symptoms,f n (%) 40 (40.4) 11 (36.7) 12 (42.9) 17 (41.5) 0.88 16 (32) 9 (37.5) 15 (60) 0.06
 High ADHD symptoms,g n (%) 45 (45.5) 13 (43.3) 13 (46.4) 19 (46.3) 0.96 22 (44) 9 (37.5) 14 (56) 0.41
 Moderate or severe insomnia symptoms,h n (%) 35 (35.4) 14 (46.7) 10 (35.7) 11 (26.8) 0.22 20 (40) 5 (20.8) 10 (40) 0.23
 Clinically relevant pain catastrophizing,i n (%) 41 (41.4) 12 (40) 13 (46.4) 16 (39) 0.81 21 (42) 9 (37.5) 11 (44) 0.89

SD = standard deviation; PEG = Pain, Enjoyment of life, and General activity scale; ADHD = attention deficit-hyperactivity disorder.

^

Proportions exclude one person who did not have health insurance.

a

Mini-International Neuropsychiatric Interview [28].

b

Score >4 for men and >3 on the Alcohol Use Disorders Identification Test [30].

c

Ref. [21].

d

Score >10 on the General Anxiety Disorder-7 [24].

e

Score >10 on the Patient Health Questionnaire-9 [23].

f

Score >14 on the PTSD CheckList—Civilian Version [25].

g

Score >14 on the World Health Organization ADHD self-report scale [26].

h

Score >15 on the Insomnia Severity Index [27].

i

Score >30 on the Pain Catastrophizing Scale [22].