Table 4.
Mediating factors and the percent of the total effect explained by each factor for those with ≥2/week nut consumption (n = 28,034).a
| Model | Beta coefficient ± standard error | Percent of total effect explained by mediator |
|---|---|---|
| Multivariable modelb for ≥ 2/week nut consumption | −0.313 ± 0.09 | – |
| Multivariable model + HbA1c | −0.368 ± 0.11 | 17.6% |
| Multivariable model + LDL | −0.374 ± 0.11 | 19.4% |
| Multivariable model + HDL | −0.375 ± 0.11 | 19.8% |
| Multivariable model + total cholesterol | −0.372 ± 0.11 | 18.8% |
| Multivariable model + hsCRP | −0.370 ± 0.11 | 18.3% |
| Multivariable model + ICAM | −0.356 ± 0.11 | 13.7% |
| Multivariable model + LDL + HDL + total cholesterol | −0.364 ± 0.11 | 16.2% |
| Multivariable model + all mediating factors | −0.334 ± 0.11 | 6.6% |
LDL = low density lipoprotein, HDL = high density lipoprotein; hsCRP = high sensitivity C reactive protein, ICAM = intercellular adhesion molecule; HbA1c = hemoglobin A1c.
a
Blood samples were collected in a subset of the population (n = 28,034).
b
Adjusted for age, body mass index, alcohol (g/day), physical activity, smoking, postmenopausal status (yes or no), and family history of myocardial infarction in parent <60 years-old (yes or no), marital status, alternate healthy eating index score.