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. 2021 Dec 12;8:61. doi: 10.1186/s40779-021-00355-y

Fig. 5.

Fig. 5

Melatonin benefits bone healing in a postradiation femoral defect model. a, b Representative three-dimensional images and quantitative analysis of micro-CT. c, d Representative images of H&E staining, Masson staining and immunochemical staining. Quantitative analysis was performed. Compared with control, *P < 0.05; compared with IR, #P < 0.05. IR irradiation, gel Matrigel, MLT melatonin, BV/TV bone volume/tissue volume, BMD bone mineral density, H&E hematoxylin–eosin, TNF-α tumor necrosis factor alpha, IL-6 interleukin-6