Inclusion criteria for systematic review	Study
Type of study	Randomized controlled trial	Yes/No/Unclear
Participants	·         Intravenous cannulation   Age (circle those that apply): ·         Children ·         Adults   Setting (circle those that apply): ·         Elective ·         Emergency ·         Healthy volunteers	Yes/No/Unclear
Types of intervention	·         Ethyl chloride ·         Other vapocoolant (state):   Control group (circle one) ·         Placebo ·         No treatment	Yes/No/Unclear     Yes/No/Unclear
Types of outcomes reported	·         Pain   ·         First attempt success rate   ·         Adverse events   ·         Participant (caregiver) satisfaction   Other:	Yes/No/Unclear