TABLE 1.

Comparison of futures between two different subtypes of PRP‐EVs. ²³ , ⁷² , ⁷³ , ⁷⁸ , ⁷⁹ , ⁸⁵

	PRP‐Exosomes	PRP‐Microvesicles
Size (diameter)	40–100 nm	100–1000 nm
Source	Multivesicular bodies (MVBs)	Plasma membrane
Formation mechanism	Endosomal sorting complex required for transport (ESCRT)	Shedding of membranes
Positive markers	CD63, CD9, TSG101, ALIX, and P‐selectin (limited)	GPIb (CD42b), P‐selectin, Pecam‐1, Peta‐3, and β1‐integrin
Pro‐coagulant sites	Negative	Annexin‐V, prothrombin, and factor X