Table 5.
Morphokinetic events (in hours) of all embryos obtained from women normal ovarian response (6–14 retrieved oocytes) and patients with high (15 or more retrieved oocytes) ovarian response—with and without polycystic ovary syndrome following the exclusion of direct uneven cleavage embryos
| Parametera | Normal response | High response without PCOS | PCOS with high response | p value |
|---|---|---|---|---|
| No. of embryos | 2556 | 950 | 116 | |
| t2 | 2.5 ± 0.9 | 2.5 ± 0.8 | 2.5 ± 1.1 | 0.183 |
| t3 | 14.8 ± 2.8 | 14.6 ± 2.6 | 14.5 ± 2.8 | 0.126 |
| t4 | 15.8 ± 3.8 | 15.7 ± 3.4 | 15.4 ± 3.3 | 0.250 |
| t5 | 27.1 ± 6.5* | 26.6 ± 6.3* | 24.7 ± 6.4 | < 0.001 |
| t8 | 34.9 ± 8.5 | 34.9 ± 8.2 | 34.3 ± 7.5 | 0.809 |
| tM | 63.3 ± 10.0* | 62.4 ± 9.8 | 60.6 ± 11.7 | 0.040 |
| tSB | 76.2 ± 8.4 | 76.2 ± 7.9 | 74.5 ± 6.6 | 0.412 |
Data presented as Mean ± SD
aTime of pronuclei fading was used as the 0 time
t(N), cleavage of N discrete cells; tM, time to morula; tSB, time to start of blastocyst formation; PCOS, polycystic ovary syndrome
*Significant difference (p < 0.05) shown in a post hoc test when compared to the PCOS with high response group