Table 5.
ALL cases must be positive for cytoplasmic CD3 positive and CD7 plus the following: | |
---|---|
Mandatory criteria (All of the criteria must be present): | |
1. CD1a negative | |
2. CD8 negative | |
3. Surface CD3 negative | |
4. TCR alpha/beta and TCR gamma/delta negative | |
5. CD5 negative or dim (<75% of blasts positive) | |
6. One or more stem cell/myeloid antigens as stated in WHO classification (CD34, HLA-DR, CD13, CD33, CD117, CD11b, and CD65) | |
Positivity of these markers do not exclude the diagnosis of ETP-ALL | CD2, CD4, CD10 |