TABLE 3.

Multivariable odds ratios for factors at the diagnostic visit associated with the fulfilment of thresholds of change in forced expiratory value in 1 s (ΔFEV₁)  >9% of predicted FEV₁ and ΔFEV₁ ≥12% and 200 mL of the initial FEV₁

	ΔFEV1 ≥9% of predicted FEV1	p-value	ΔFEV1 ≥12% of the initial FEV1+200 mL	p-value
Age ≥45 years	1.54 (0.73–3.22)	0.258	1.72 (0.77–3.85)	0.190
Male	0.71 (0.33–1.50)	0.365	0.43 (0.19–1.00)	0.050
Symptoms, AQ20	1.10 (0.97–1.14)	0.228	1.02 (0.94–1.11)	0.630
Total IgE <100 kU·L−1	2.06 (0.97–4.37)	0.060	2.84 (1.24–6.51)	0.014
Blood eosinophils >0.25×109 per L	1.90 (0.89–4.10)	0.097	2.55 (1.10–5.88)	0.029
Post-bronchodilator FEV1/FVC<0.7 and ≥10 pack-years	0.26 (0.60–1.11)	0.690	0.39 (0.11–1.43)	0.155
Pre-bronchodilator FEV1 <80% predicted#	6.03 (2.11–17.21)	<0.001	15.93 (5.00–50.80)	<0.001
Pre-bronchodilator FVC >90% predicted#	4.71 (1.68–13.18)	0.003	2.90 (0.99–8.53)	0.053

Ig: immunoglobulin; FVC: forced vital capacity; FEV₁: forced expiratory volume in 1 s; AQ20: Airways Questionnaire 20. ^#: Measured from the spirometry with highest reversibility. Data are presented as ORs (95% CIs). BMI and smoking were not significantly associated with the thresholds and were excluded from the model. Statistically significant associations are presented in bold.