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. 2021 Dec 13;7(4):00247-2021. doi: 10.1183/23120541.00247-2021

FIGURE 7.

FIGURE 7

Summary of the observed changes in different chloride channels/transporters expression and differentiation markers upon exposure to cytokines. The heatmap was generated based on the results shown in figures 1, 2 and 6. Data were rescaled between 0 and 1, with lower and higher expression levels represented in white and red, respectively. Inflammatory mediators are grouped into clusters according to the relative expression levels of all the proteins analysed. Dashed lines separate the chloride channels/transporters, differentiation markers and mucins. IL: interleukin; Con: control; TNF: tumour necrosis factor; CFTR: cystic fibrosis transmembrane conductance regulator; TMEM16A: transmembrane protein 16A; SLC26A: solute carrier family 26.