Images for a 52-year-old female patient with numerous enhancing lesions using MPRAGE (A,D), PETRA (B,E), and DANTE-SPACE (C,F). The enhancing lesions obtained with DANTE-SPACE (C,F) show better-defined margins and contrast between lesions and surrounding parenchyma compared with those obtained with MPRAGE (A,D) and PETRA (B,E). More enhancing lesions were detected with DANTE-SPACE [arrows in (C,F)] than with MPRAGE and PETRA. MPRAGE, magnetization-prepared rapid acquisition with gradient echo; PETRA, pointwise encoding time reduction with radial acquisition; DANTE-SPACE, delay alternating with nutation for tailored excitation sampling perfection with application-optimized contrasts using different flip angle evolution.