Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: (a) methyl iodide, dry DMF, rt; (b) (cyclo)alkyl-/arylalkyl bromide, anhydrous potassium carbonate, dry DMF, rt; (c) (i) cesium carbonate, MeOH, rt, (ii) methyl iodide, dry DMF, 0 °C → rt; (d) ethyl propiolate, tetrabutylammonium fluoride, dry THF, rt; and (e) potassium hydroxide 2 N, ethanol, rt.
