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. 2021 Nov 30;64(23):17079–17097. doi: 10.1021/acs.jmedchem.1c00946

Table 3. Structure–Activity Relationships for Polar Amide Groups in the Extended Pocketb.

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a

Solubility measurement by NMR assay.

b

Solubility measurement by high-performance liquid chromatography (HPLC). nc, not conducted.