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Effect of PDK1 silencing on lung function of rats in each group. (A) Lung injury score; (B) minute ventilation (mL/kg); (C) lung volume (mL); (D) airway resistance. *, P<0.05 vs. the sham group; #, P<0.05 vs. ALI model group. PDK1, 3-phosphoinositide-dependent kinase 1; LPS, lipopolysaccharide; mRNA, messenger RNA; ALI, acute lung injury.
