Table 1.
Dysregulated metabolites between the DHEA+Sham and DHEA+BAT groups.
| Class | Name | VIP | p-value | Fold change |
|---|---|---|---|---|
| Sphingolipids | N-palmitoyl-d-erythro-sphingosine | 1.32187 | 0.048360335 | 0.701984889 |
| Dehydes | Pyruvaldehyde | 1.4637 | 0.002293146 | 0.641374704 |
| Amino acids | dl-β-Leucine | 1.03371 | 0.011904801 | 0.257662834 |
| l-Glutamine | 1.38227 | 0.006913317 | 0.627002081 | |
| Cholic acid | Taurocholic acid | 1.03748 | 0.004480277 | 7.0752304 |
| Fatty acyls | 1-Linoleoyl glycerol | 1.13363 | 0.008396951 | 1.889026271 |
| Fatty esters | Icosadienoic acid | 1.23869 | 0.00649719 | 3.345072531 |
| Glycerophosphocholines | Lyso-PAF C-16 | 1.3197 | 0.03773069 | 1.525340715 |
| PC(P-15:0/0:0) | 1.09853 | 0.024659805 | 1.587064544 | |
| Glycerophosphoethanolamines | LysoPE(0:0/22:4(7Z,10Z,13Z,16Z)) | 1.474 | 0.005592236 | 1.897683421 |
| Glycerophosphoinositols | PI(18:0/22:5(4Z,7Z,10Z,13Z,16Z)) | 1.20277 | 0.003526964 | 0.324269691 |
| PI(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) | 1.45847 | 0.013576691 | 0.315352317 | |
| PS(18:0/22:5(7Z,10Z,13Z,16Z,19Z)) | 1.16498 | 0.003497396 | 0.585825926 | |
| Glycerophosphates | beta-Glycerophosphoricacid | 1.16314 | 0.004377947 | 0.502442175 |
| Peptides | Asp Ile Lys Arg | 1.03604 | 0.030470895 | 1.509817996 |
| Cys Gln Trp Trp | 1.24675 | 0.002413147 | 2.344734335 | |
| Leu Asp | 1.22868 | 0.047455033 | 4.396481329 | |
| Phe Phe Arg Arg | 1.29797 | 0.000174435 | 1.620741001 | |
| Tyr Lys Val Glu Ile | 1.26152 | 0.0108703 | 1.614132279 | |
| Phenylsulfates | 4-Ethylphenylsulfate | 1.66923 | 0.002512745 | 1.917318971 |
| TCA | d-(+)-Malic acid | 1.14599 | 0.030182727 | 1.516545227 |
| Unclassified | Glc-GP(18:0/20:4(5Z,8Z,11Z,14Z)) | 1.33843 | 0.001968024 | 0.390099725 |
DHEA, dehydroepiandrosterone; BAT, brown adipose tissue; VIP, variable importance in projection; TCA, trichloroacetic acid.