Table 1.
Characteristics and clinical outcomes of patients with VV-ECMO or VA-ECMO.
|
VV-ECMO
(n = 15) |
VA-ECMO
(n = 39) |
|
|---|---|---|
| Age (year) | 64 (51–71) | 63 (52–69) |
| Height (cm) | 164 (159–168) | 168 (157–174) |
| Weight (kg) | 62.9 (57.0–75.2) | 67.4 (56.3–82.3) |
| Sex (female/male) | 6/9 | 7/32 |
| APACHE II score | 31 (26–40) | 29 (24–36) |
| SAVE score | - | −8 (−10 to −2) |
| RESP score | 0 (−3 to 4) | - |
| RRT, n (%) | 4 (27%) | 22 (56%) |
| ECMO indication | ||
| E-CPR | - | 16 |
| Heart failure | - | 17 |
| Postcardiotomy | - | 4 |
| Septic shock | - | 2 |
| ARDS | 15 | - |
| EAA level | ||
| T1 median (IQR) | 0.44 (0.31–0.71) | 0.33 (0.22–0.50) |
| T2 median (IQR) | 0.50 (0.36–0.66) | 0.38 (0.28–0.52) |
| T3 median (IQR) | 0.50 (0.33–0.78) | 0.40 (0.23–0.57) |
| T4 median (IQR) | 0.49 (0.37–0.59) | 0.44 (0.29–0.56) |
| ECMO free daysa | 0 (0–17) | 14 (0–24) |
| ICU free daysb | 0 | 0 (0–2) |
| 30-day survival, n (%) | 11 (73%) | 21 (54%) |
Data are presented as medians (interquartile ranges, IQRs), numbers, and percentages as appropriate. Four study time points: within 24 h (T1) and 25–48 (T2), 49–72 (T3), and 73–96 h (T4) after ECMO initiation. APACHE II, Acute Physiology and Chronic Health Evaluation II; ARDS, acute respiratory distress syndrome; EAA, endotoxin activity assay; ECMO, extracorporeal membrane oxygenation; E-CPR, extracorporeal cardiopulmonary resuscitation; ICU, intensive care unit; IQR, interquartile range; RRT, renal replacement therapy; SAVE, Survival after Venoarterial ECMO; RESP, Respiratory ECMO Survival Prediction; VA-ECMO, venoarterial ECMO; VV-ECMO, venovenous ECMO.
ECMO free days were defined as days free from ECMO support, between ECMO initiation and day 30.
ICU free days were defined as days bot in the ICU, between ECMO initiation and day 30.