Table 2.
VA-ECMO | 30-day survivors (n = 21) | 30-day non-survivors (n = 18) | P values |
---|---|---|---|
Age (year) | 65 (55–71) | 62 (49–66) | 0.367 |
Sex (female/male) | 2/19 | 5/13 | |
APACHE II score | 27 (24–32) | 36 (27–39) | 0.020 |
SAVE score | −5 (−9–−1) | −10 (−15–−7) | 0.003 |
ECMO free daysa | 22 (17–26) | 1 (0–13) | 0.001 |
ICU free daysb | 0 (0–15) | 0 | 0.009 |
T1 (within 24 h) | |||
EAA | 0.38 (0.20–0.51) | 0.29 (0.20–0.46) | 0.319 |
WBC (k/μL) | 12.2 (9.5–17.4) | 12.1 (9.7–15.9) | 0.988 |
Inotropic score | 4.1 (0–20.7) | 12.9 (1.9–19.4) | 0.483 |
Lactate (mmol/L) | 10.1 (3.4–13.5) | 9.5 (7.7–13.1) | 0.478 |
T2 (25–48 h) | |||
EAA | 0.38 (0.20–0.52) | 0.38 (0.33–0.52) | 0.660 |
WBC (k/μL) | 12.1 (10.6–15.3) | 12.8 (8.8–15.6) | 0.885 |
Inotropic score | 4.6 (0.7–11.5) | 9.2 (3.3–18.8) | 0.147 |
Lactate (mmol/L) | 2.9 (1.7–4.5) | 3.1 (2.0–4.4) | 0.641 |
T3 (49–72 h) | |||
EAA | 0.31 (0.19–0.51) | 0.49 (0.37–0.63) | 0.024 |
WBC (k/μL) | 12.3 (9.0–15.2) | 10.4 (7.9–12.2) | 0.128 |
Inotropic score | 2.3 (0.0–8.1) | 7.5 (1.1–13.9) | 0.220 |
Lactate (mmol/L) | 1.9 (1.4–3.0) | 2.5 (1.8–5.3) | 0.056 |
T4 (73–96 h) | |||
EAA | 0.41 (0.29–0.52) | 0.49 (0.29–0.61) | 0.391 |
WBC (k/μL) | 10.1 (8.8–13.5) | 11.3 (7.9–11.9) | 0.977 |
Inotropic score | 0.9 (0–7.9) | 3.2 (0–15.4) | 0.427 |
Lactate (mmol/L) | 1.8 (1.2–2.5) | 2.5 (1.4–4.0) | 0.126 |
Data are presented as medians (interquartile ranges), numbers, and percentages as appropriate. Study time points (T1–T4) represent the time after ECMO initiation. APACHE II, Acute Physiology and Chronic Health Evaluation II; EAA, endotoxin activity assay; ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; SAVE, Survival after Venoarterial ECMO; VA-ECMO, venoarterial ECMO; WBC, white blood cell.
ECMO free days were defined as days free from ECMO support from ECMO initiation until day 30.
ICU free days were defined as days bot in the ICU, between ECMO initiation and day 30.