Table 2.
The main genetic findings of 9 MEITL cases.
| case | Somatic mutations | Copy number variations | |||||
|---|---|---|---|---|---|---|---|
| STAT5B | TP53 | JAK3 | SETD2 | STAT5A | chromosomal arms | CNV type | |
| 1 | p.R248Q | p.M511I |
p.N642H p.G472S |
8p,8q,9p,12p,20p | deletion | ||
| 4q,7q,9q | amplification | ||||||
| 2 | p.N642H | p.I232Sfs*15 | 4p,4q,7p,10p,10q,15q,18p | deletion | |||
| 1q,9q,19q | amplification | ||||||
| 3 | p.Y665F | p.V147Afs*19 | p.A573V |
p.E1772_I1781delinsV p.D2004Ifs*13 |
4p,7p,8p,18p,21q | deletion | |
| 7q,8q,9q,12p,12q,18q,22q | amplification | ||||||
| 4 | p.Q701L | 6p,7p,18p | deletion | ||||
| 9q,21q | amplification | ||||||
| 5 | 7p,8p | deletion | |||||
| 7q,9q,19q,19p | amplification | ||||||
| 6 | p.A766V | p.G105C | p.R657Q | 1q,7q,9q,19q,19p | amplification | ||
| 7 | p.N642H | p.S1572* | |||||
| 8 | |||||||
| 9 | 21q | deletion | |||||
| 1q,6p,8q,9q,20q,22q | amplification | ||||||