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. 2021 Dec 12;11:205. doi: 10.1186/s13578-021-00716-z

Table 1.

Characteristics of the sample population

All
(n = 5131)
LOY No
(n = 3739)
LOY Yes
(n = 1392)
p-value*

Age at Enrolment

Mean (SD)

74.9 (4.18) 74.4 (3.84) 76.3 (4.73)  < 0.001
Smoking  < 0.001
 Never 2253 (43.9%) 1680 (44.9%) 573 (41.2%)
 Former 2699 (52.6%) 1952 (52.2%) 747 (53.7%)
 Current 179 (3.5%) 107 (2.9%) 72 (5.2%)
Alcohol 0.04
 Never 461 (9.0%) 359 (9.6%) 102 (7.3%)
 Former 294 (5.7%) 211 (5.6%) 83 (6.0%)
 Current 4376 (85.3%) 3169 (84.8%) 1207 (86.7%)
Treatment 0.57
 Placebo 2564 (50.0%) 1878 (50.2%) 686 (49.3%)
 Aspirin 2567 (50.0%) 1861 (49.8%) 706 (50.7%)
BMI (kg/m2)
 Normal 1063 (21.0%) 754 (20.5%) 309 (22.5%) 0.07
 Underweight 38 (0.8%) 23 (0.6%) 15 (1.1%)
 Overweight 2633 (52.1%) 1921 (52.2%) 712 (51.9%)
 Obese 1298 (25.7%) 969 (26.3%) 329 (24.0%)
 Missing 18 (0.4%) 12 (0.3%) 6 (0.4%)

* Using the LOY binary variable, t-test or chi-square test we performed for continuous and categorical variables, respectively