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. 2021 Dec 13;239:123147. doi: 10.1016/j.talanta.2021.123147

Fig. 2.

Fig. 2

The Concentration-dependent effect of Spike S1 binding on charge transfer resistance. A) Representative Nyquist plots from measurements of a bare gold electrode (denoted ‘Bare GE’, black squares), S1Ab-functionalized electrode (‘Bare GE + S1Ab’, red circles), and S1Ab-functionalized electrode after incubation in a solution containing 100 μg/mL purified S1 (‘Bare GE + S1Ab + S1 protein’, green triangles); B) the corresponding Rct values averaged over 3–5 repetitions. C) Relative Rct change obtained for different S1-RBD concentrations (0.015, 1.55, 15.5, 155 and 1550 μg/mL). ΔRct values were calculated by: [Rct(RBD)/Rct(S1Ab)]-1 and averaged over 3 to 5 repetitions; D) Dependence of %ΔRct on RBD concentration. Error bars represent ±SD. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)