Adjusted Odds Ratios for Global Cortex Florbetapir SUVRs > 1.2 by Number of Vascular Risk Factors, Midlife Through Late Life Adjusted odds ratios (with 95% confidence intervals as error bars) are shown for number of vascular risk factors for visits 1 (at midlife) through 5 (at late life) for standardized uptake value ratios (SUVRs) > 1.2. Models are adjusted for age (at Visit 5, 2011–13), sex, race, education level, and apolipoprotein E ε4 genotype. Vascular risk factors include body mass index ≥30 kg/m2, current smoking, hypertension, diabetes, and total serum cholesterol ≥200 mg/dL. Republished with permission from Gottesman RF, Schneider AL, Zhou Y, et al. Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition. JAMA. 2017 Apr 11;317(14):1443–1450.