TABLE 2.

Group differences in HRR after the 6‐minute walk test adjusted for %Pred 6MWT distance, resting heart rate, body mass index and age

Variable	SARS‐CoV‐2 (n = 28)	Control (n = 16)	P‐value
Unadjusted			0.185
HRR1min	−22 ± 10	−29 ± 10	0.024*
HRR2min	−28 ± 12	−36 ± 11	0.024*
HRR3min	−30 ± 13	−39 ± 13	0.043*
HRR4min	−31 ± 14	−42 ± 12	0.019*
HRR5min	−31 ± 14	−43 ± 13	0.012*
Adjusted for %Pred 6MWT distance			0.202
HRR1min	−22 ± 9	−28 ± 9	0.029*
HRR2min	−28 ± 10	−35 ± 10	0.027*
HRR3min	−31 ± 11	−37 ± 11	0.056
HRR4min	−32 ± 12	−41 ± 12	0.024*
HRR5min	−32 ± 12	−42 ± 12	0.013*
Adjusted for resting HR			0.228
HRR1min	−22 ± 9	−28 ± 9	0.031*
HRR2min	−28 ± 11	−36 ± 11	0.033*
HRR3min	−30 ± 13	−38 ± 13	0.063
HRR4min	−32 ± 13	−41 ± 13	0.028*
HRR5min	−32 ± 13	−42 ± 13	0.018*
Adjusted for BMI			0.206
HRR1min	−22 ± 10	−29 ± 10	0.027*
HRR2min	−28 ± 11	−36 ± 11	0.027*
HRR3min	−30 ± 13	−38 ± 13	0.050*
HRR4min	−31 ± 14	−42 ± 14	0.023*
HRR5min	−32 ± 14	−42 ± 14	0.014*
Adjusted for age			0.224
HRR1min	−22 ± 10	−29 ± 10	0.032*
HRR2min	−28 ± 12	−36 ± 12	0.035*
HRR3min	−30 ± 13	−38 ± 14	0.054
HRR4min	−31 ± 14	−41 ± 14	0.026*
HRR5min	−32 ± 14	−42 ± 14	0.017*

Abbreviations: BMI, body mass index; HR, heart rate; HRR_1min, HRR_2min, etc., the difference in HR immediately post‐6MWT compared with each minute of recovery; SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2; 6MWT, 6‐minute walk test; %Pred 6MWT distance, distance travelled during the 6MWT normalized to a reference sample using predictive equations provided by Casanova et al. (2011). Note. The P‐value shown in bold is the omnibus test statistic for MANOVA/MANCOVA.

^* P ≤ 0.05 between SARS‐CoV‐2 and control groups.