TABLE 1.
Characteristics of Control and NG-HTN rats used in the studies.
| Parameters | Control (n = 6) | NG-HTN (n = 6) |
| Body weight; BW (g) | 331.1 ± 11.2 | 235.3 ± 18.2* |
| Heart weight; HW (g) | 0.94 ± 0.02 | 1.03 ± 0.03* |
| HW/BW × 1000 | 2.86 ± 0.06 | 4.54 ± 0.45* |
| Heart rate; HR (bpm) | 372 ± 13 | 386 ± 11 |
| +dP/dt (mmHg/s) | 7258 ± 486 | 7778 ± 404 |
| −dP/dt (mmHg/s) | 7987 ± 860 | 8387 ± 561 |
| MAP (mmHG) | 83 ± 4 | 125 ± 8 |
| LVEDP (mmHg) | 2.0 ± 0.3 | 3.6 ± 0.5 |
| E/A | 1.5 ± 0.2 | 1.2 ± 0.1* |
| %EF | 69 ± 5% | 67 ± 2% |
| −dP/dt with ISO | −11,765 ± 708 | −8581 ± 661* |
LVEDP, left ventricular end-diastolic pressure; MAP, mean arterial pressure; HR, heart rate; EF, ejection fraction; ISO, Isoproterenol. Data are represented as mean ± SE of six rats in each group. *P < 0.05 sham vs. NG-HTN. Student’s t-test.