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Probability density of gyration radius computed for WT and mutants of α-syn for the complete conformational ensemble (top panel), the ensemble of state HB (middle panel), and the ensemble of state B (bottom panel). The color code is WT (black), A30P (purple), E46K (turquoise), and A53T (orange). State B represents 40% of conformations for WT, A30P, and E46K and 25% for A53T (see text).
