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TFE3 overexpression rescues the autophagy defects of dopaminergic neurons in MPTP-treated mice. (A, C and E) Detection of LC3 (green, A), Lamp1 (green, C) and CatD (green, E) in dopaminergic neurons (red) of the SN from Saline- and MPTP-injected mice overexpressing Flag or TFE3. Scale bars: 20 μm. (B, D and F) Quantitative data are shown. n = 3-4 per group. Data are expressed as the mean ± SEM. *p < 0.05, **p < 0.01, ####p < 0.0001, ANOVA followed by Tukey’s multiple comparisons test.
