Figure 3.

Functional enrichment of pathways enriched in liver and muscle and expression levels of genes in commonly dysregulated pathways. Heat map (top left) representing the differentially regulated gene pathways in liver and muscle from prenatal testosterone (T)-treated animals compared against control animals and enriched at a false discovery rate (FDR) of less than 0.01. The bar plots (bottom left) represent the number of gene pathways differentially modulated that are unique to either liver and muscle or commonly dysregulated in both tissues. Heat map (right) showing genes involved in the mitochondrial membrane pathway that is dysregulated both in liver (C = 4, T = 5) and muscle (C = 5, T = 5). The genes associated with the gene pathway in controls animals and prenatal T–treated animals are plotted along a gradient of colors, with blue representing the highest and yellow the lowest normalized counts.