Kaplan–Meier curves comparing DFI (in days) of dogs in relation to cMM CSPG4-positivity score. (A) DFI of vaccinated dogs (group A) bearing a cMM with CSPG4-positivity score ≥5 (black line) or <5 (black dotted line). (B, C) DFI of vaccinated dogs (group A) bearing a cMM with CSPG4-positivity score ≥5 (black line) in comparison with DFI of (B) the entire population of non-vaccinated dogs (group B, grey dotted line; * log-rank test P = 0.0167) or of (C) non-vaccinated dogs bearing a cMM with CSPG4-positivity score ≥5 (group B, grey line; * log-rank test P = 0.0249). (D, E) DFI of vaccinated dogs (group A) bearing a cMM with CSPG4-positivity score <5 (black dotted line) in comparison with DFI of (D) the entire population of non-vaccinated dogs (group B, grey dotted line) or of (E) non-vaccinated dogs bearing a cMM with CSPG4-positivity score <5 (group B, grey line).