Table 2.
Clinical and Sociodemographic Characteristics of Patients with PSD and Non-PSD at Discharge
| Variables | PSD Patients (n=249) | Non-PSD Patients (n=269) | P-Value |
|---|---|---|---|
| Serum LDH level (U/L), median (IQR) | 179.0 (158.0, 213.0) | 168.0 (149.0, 195.0) | 0.001 |
| Sociodemographic parameters | |||
| Age (years), median (IQR) | 61.0 (54.0, 67.0) | 59.0 (51.0, 65.0) | <0.001 |
| Females, n (%) | 57 (22.89) | 58 (21.56) | 0.716 |
| BMI (kg/m2), median (IQR) | 24.67 (22.86, 27.18) | 24.67 (22.76, 26.77) | 0.273 |
| Married, n (%) | 239 (95.98) | 254 (94.42) | 0.408 |
| Educational level | 0.004 | ||
| Junior middle school and below, n (%) | 164 (65.86) | 163 (60.59) | |
| Senior high/polytechnic school, n (%) | 62 (24.90) | 54 (20.07) | |
| Bachelor and above, n (%) | 23 (9.24) | 52 (19.33) | |
| Vascular risk factors | |||
| History of smoking, n (%) | 142 (57.03) | 167 (62.08) | 0.241 |
| History of drinking, n (%) | 151 (60.64) | 151 (56.13) | 0.298 |
| History of diabetes, n (%) | 61 (24.50) | 72 (26.77) | 0.555 |
| History of hypertension, n (%) | 136 (54.62) | 160 (59.48) | 0.264 |
| History of hyperlipidemia, n (%) | 56 (22.49) | 66 (24.54) | 0.584 |
| History of coronary artery diseases, n (%) | 30 (12.05) | 21 (7.81) | 0.105 |
| History of previous stroke, n (%) | 49 (19.68) | 45 (16.73) | 0.384 |
| History of surgery, n (%) | 73 (29.32) | 82 (30.48) | 0.772 |
| History of atrial fibrillation, n (%) | 8 (3.21) | 12 (4.46) | 0.461 |
| Clinical characteristics | |||
| NIHSS score, median (IQR) | 8 (5,10) | 2 (1, 4) | <0.001 |
| BI score, median (IQR) | 95 (65, 100) | 100 (80, 100) | <0.001 |
| mRS score, median (IQR) | 4 (3, 4) | 2 (1, 3) | <0.001 |
| HRSD score, median (IQR) | 13 (10, 18) | 3 (2, 5) | <0.001 |
| Hospitalization days, median (IQR) | 12 (9, 15) | 9 (8, 12) | <0.001 |
| Serum biochemistry | |||
| CRP (mg/L), median (IQR) | 2.40 (0.75, 7.25) | 2.30 (0.60, 7.25) | 0.319 |
| IL-1β (pg/mL), median (IQR) | 63.92 (30.00, 156.16) | 62.03 (22.86, 163.83) | 0.623 |
| IL-6 (pg/mL), median (IQR) | 5.75 (2.29, 9.95) | 6.00 (2.69, 9.37) | 0.947 |
| IL-10 (pg/mL), median (IQR) | 7.76 (2.14, 21.78) | 9.16 (2.74, 21.60) | 0.262 |
| IL-18 (pg/mL), median (IQR) | 1959.33 (951.89, 4530.10) | 1975.92 (968.56, 4553.51) | 0.922 |
| TNF-α (pg/mL), median (IQR) | 40.23 (22.12, 56.01) | 40.41 (25.22, 58.12) | 0.433 |
| BDNF (ng/mL), median (IQR) | 3.13 (1.94, 6.34) | 3.82 (2.16, 8.44) | 0.028 |
| IFN-γ (pg/mL), median (IQR) | 4.56 (1.89, 9.60) | 3.86 (1.65, 8.80) | 0.347 |