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. 2021 Dec 6;2021:5881321. doi: 10.1155/2021/5881321

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Copyright © 2021 Shuang Liu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of SKN on AMPK-Nrf2-HO-1 signaling in ox-LDL-treated HUVECs. (a) Results of Western blot and analysis of AMPK and p-AMPK in ox-LDL-treated HUVECs. (b) Results of Western blot and analysis of Nrf2 in ox-LDL-treated HUVECs. (c) Results of Western blot and analysis of HO-1 in ox-LDL-treated HUVECs. (d) Relative ROS production of cells in different groups. (e) Cell viability in different groups. (f) Cell apoptosis rate in ox-LDL-treated HUVECs. Data are expressed as mean ± SD, n = 3. ^∗P < 0.05 vs. the control group. ^#P < 0.05 vs. the ox-LDL group. ΔP < 0.05 vs. the SKN + ox-LDL group.