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. 2021 Dec 6;2021:9570971. doi: 10.1155/2021/9570971

Figure 1.

Figure 1

Effects of sRAGE on cardiac function and infarction size following myocardial ischemia-reperfusion in mice. (a) Representative M-mode echocardiography images of the long axis after ischemia for 30 minutes and reperfusion for 24 hours in mice. (b) Quantification of the left ventricular cardiac output (ml/min) of each group. (c) Quantification of the left ventricular stroke volume (μl) of each group. (d) Quantification of the left ventricular ejection fraction (%) of each group. (e) Quantification of the left ventricular fractional shortening (%) of each group. (f) Heart rate (BPM) value of each group. (g) TTC staining pictures of the heart after I/R or sham operation. (h) Infarction area/total area of the sagittal plane of the left ventricle (%) of each group. Data are expressed as the mean ± SEM (n ≥ 6 mice per group). ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ns: no significance.