Figure 2.

Effects of sRAGE on apoptosis and necrosis following myocardial ischemia-reperfusion in mice. (a) Representative TUNEL staining image in the myocardium. The target protein was shown in red, indicating apoptosis-positive cardiomyocyte. The scale bar is 20 μm. (b) Quantitative statistics of TUNEL staining is shown above. (c) The detection of the serum cTnI level (ng/ml). Data are expressed as the mean ± SEM (n = 6 mice per group). ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001; ns: no significance.