Table 2.
Echocardiographic variables at baseline
| ALL | Control | Febuxostat | P value | |
|---|---|---|---|---|
| Number | 65 | 34 | 31 | |
| Echocardiographic variables | ||||
| TMF-E | 66 [57,80] | 64 [57,80] | 66 [58,81] | 0.480 |
| Averaged e’ | 7.65 [6.25, 9.10] | 7.75 [6.95, 10.20] | 6.09 [4.80, 7.99] | 0.028 |
| Averaged E/e’ | 8.04 [7.01, 10.01] | 7.90 [6.32, 9.08] | 9.18 [7.86, 11.67] | 0.032 |
| TMF-A | 79 [67,91] | 83 [69,93] | 74 [66,89] | 0.430 |
| E/A | 0.79 [0.74, 1.11] | 0.77 [0.69, 1.13] | 0.86 [0.76, 1.08] | 0.302 |
| Deceleration time | 217 [192, 241] | 220 [200, 247] | 210 [186, 234] | 0.349 |
| LV end-diastolic dimension | 48.0 [45.0, 52.0] | 48.2 [44.9, 52.3] | 47.0 [45.0, 52.0] | 0.804 |
| LV end-systolic dimension | 30.1 [27.7, 34.1] | 31.0 [27.7, 34.0] | 30.0 [27.8, 36.3] | 0.946 |
| LV ejection fraction | 63.9 [56.4, 69.0] | 64.0 [58.5, 69.0] | 63.0 [56.4, 69.0] | 0.602 |
| LV mass index | 101 [88, 123] | 102 [86, 121] | 99 [91, 128] | 0.611 |
| Categories of LV hypertrophy | 0.774 | |||
| Normal | 42.9% | 47.6% | 38.1% | |
| Concentric remodeling | 31.0% | 23.8% | 38.1% | |
| Concentric hypertrophy | 11.9% | 14.3% | 9.5% | |
| Eccentric hypertrophy | 14.3% | 14.3% | 14.3% | |
| LA volume | 58 [45,77] | 59 [42,77] | 54 [49,70] | 0.923 |
TMF-E early diastolic transmitral flow wave, e’ early mitral annular velocity, TMF-A late diastolic transmitral flow wave, LV left ventricular, LA, left atrial.
Data are presented as median (interquartile range).