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. 2021 Dec 13;7:114. doi: 10.1038/s41531-021-00259-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Schematic of the buried food pellet test. b Latency to locate a food pellet that is buried (Olfactory) or on the surface of the bedding (Visual) in control (n = 21) and hα-syn (n = 18) mice. c–e Olfactory preference/avoidance test. c Schematic of the test chamber. d Time spent by control (n = 11) and hα-syn mice (n = 13) in the chamber with peanut butter (blue) versus mineral oil (green) in the olfactory preference test. e Time spent by mice (n = 11 for control group and n = 13 for hα-syn group mice) in the chamber with TMT (blue) versus mineral oil (green) in the olfactory avoidance test. The RTPP index indicates the degree of preference for peanut butter (d) or TMT (e). *p < 0.05; ***p < 0.001; n.s. not significant. Data are presented as mean ± SEM.