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. 2021 Dec 13;7:114. doi: 10.1038/s41531-021-00259-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a, b Low-magnification (scale bars = 100 μm) (a) and high-magnification (scale bars = 20 μm) (b) images showing granule cells labeled with mCherry in the OB. EPL external plexiform layer, MCL mitral cell layer, GCL granule cell layer. c Schematic of the light-evoked IPSC electrophysiological recording. d Representative IPSCs recorded from mitral cells when 2 Hz (left) and 20 Hz (right) light illumination was applied. e Representative traces of paired-pulse IPSCs. f Quantitative analysis of the paired-pulse depression of light-evoked IPSCs recorded from mitral cells from the control and hα-syn groups (control: 19 cells from 8 mice; hα-syn: 14 cells from 6 mice). g Quantitative analysis of the amplitude of the first light-evoked IPSC. h Representative current injection-evoked APs in granule cells. i–k Quantitative analysis of the frequency (i), onset latency (j), and membrane potential (k) elicited by positive current injections (13 cells from 5 mice for the control and hα-syn groups, respectively). mIPSC miniature inhibitory postsynaptic current; *p < 0.05; **p < 0.01; n.s. not significant. Data are presented as mean ± SEM.