Table 1.
Demographic and clinical description of participants included in the test library.
| Total (N, %) | Xpert MTB/RIF results | P-value╪ | ||
|---|---|---|---|---|
| Negative (N, %) | Positive (N, %) | |||
| All participants | 1032 | 899 (87.1%) | 133 (12.9%) | N/A |
| Demographic factors | ||||
| Gender | ||||
| Male | 712 (69.0%) | 605 (85.0%) | 107 (15.0%) | 0.002 |
| Female | 320 (31.0%) | 294 (91.9%) | 26 (8.1%) | |
| Age, median (IQR) | 62 (53–70) | 62 (54–71) | 59 (48–68) | 0.004 |
| 15–54 years | 291 (28.2%) | 240 (82.5%) | 51 (17.5%) | 0.005 |
| ≥ 55 years | 741 (71.8%) | 659 (88.9%) | 82 (11.1%) | |
| Health insurance | 881 (85.4%) | 769 (87.3%) | 112 (12.7%) | 0.686 |
| Residency status | ||||
| Long-term resident of HCMC | 896 (86.8%) | 783 (87.4%) | 113 (12.6%) | 0.497 |
| Recent migrant to HCMC | 136 (13.2%) | 116 (85.3%) | 20 (14.7%) | |
| Presence of TB symptoms | ||||
| Cough (C) | ||||
| No Cough | 455 (44.1%) | 420 (92.3%) | 35 (7.7%) | < 0.001 |
| < 2 weeks | 175 (17.0%) | 148 (84.6%) | 27 (15.4%) | |
| ≥ 2 weeks | 402 (39.0%) | 331 (82.3%) | 71 (17.7%) | |
| Fever (F) | 56 (5.4%) | 43 (76.8%) | 13 (23.2%) | 0.018 |
| Weight loss (WL) | 113 (10.9%) | 94 (83.2%) | 19 (16.8%) | 0.187 |
| Night sweats (NS) | 64 (6.2%) | 59 (92.2%) | 5 (7.8%) | 0.211 |
| 4 Symptoms: C + F + WL + NS | 638 (61.8%) | 534 (83.7%) | 104 (16.3%) | < 0.001 |
| Chest pain | 229 (22.2%) | 199 (86.9%) | 30 (13.1%) | 0.913 |
| Fatigue | 235 (22.8%) | 189 (80.4%) | 46 (19.6%) | < 0.001 |
| Any TB symptom | 727 (70.4%) | 614 (84.5%) | 113 (15.5%) | < 0.001 |
| Cough plus any one symptom | 291 (28.2%) | 238 (81.8%) | 53 (18.2%) | 0.001 |
| Any TB symptom except cough | 441 (42.7%) | 373 (84.6%) | 68 (15.4%) | 0.036 |
| TB risk factors | ||||
| Contact of TB patient | 64 (6.2%) | 48 (75.0%) | 16 (25.0%) | 0.003 |
| Past history of TB | 346 (33.5%) | 294 (85.0%) | 52 (15.0%) | 0.145 |
| Diabetes | 103 (10.0%) | 87 (84.5%) | 16 (15.5%) | 0.398 |
| HIV | 2 (0.2%) | 2 (100.0%) | 0 (0.0%) | 0.586 |
| X-ray factors | ||||
| Radiography system | ||||
| JPI Healthcare | 493 (47.8%) | 464 (94.1%) | 29 (6.3%) | < 0.001 |
| DRTECH | 539 (52.2%) | 435 (80.7%) | 104 (23.9%) | |
| Abnormal CXR | ||||
| Expert Reader | 647 (62.7%) | 520 (80.4%) | 127 (19.6%) | 0.338 |
| Intermediate Reader | 495 (48.0%) | 386 (78.0%) | 109 (22.0%) | |
| Normal/Clear CXR | ||||
| Expert Reader | 385 (37.3%) | 379 (98.4%) | 6 (1.6%) | 0.014 |
| Intermediate Reader | 537 (52.0%) | 513 (95.5%) | 24 (4.5%) | |
Significant values are in bold.
╪Chi-squared test.