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. 2021 Dec 13;11:23867. doi: 10.1038/s41598-021-03367-9

Table 1.

Pyrethroid resistance in relation to pyrethroid use per country.

Four categories of conditionsa Number of eligible countries, by year % per category Pb
Category Confirmed resistance Pyrethroids in use 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2010–2014 2015–2019
1 Yes Yes 7 8 6 9 8 4 7 5 3 1 34.2% 27.4% n.s
2 Yes No 3 3 6 5 7 9 9 5 3 6 21.6% 43.8% 0.002
3 No Yes 10 8 12 7 9 9 2 3 4 2 41.4% 27.4% 0.05
4 No No 0 0 0 3 0 1 0 0 0 0 2.7% 1.4% n.s
Sum 20 19 24 24 24 23 18 13 10 9 100.0% 100.0%

Presented is the number of eligible countries in each category per year. ‘Confirmed resistance’ refers to < 90% mortality of anophelines in insecticide susceptibility bioassays for pyrethroids24. ‘Pyrethroids in use’ refers to use in IRS for malaria control.

aCategories: 1, confirmed resistance, pyrethroids in use; 2, confirmed resistance, no pyrethroids in use; 3, no confirmed resistance, pyrethroids in use; 4, no confirmed resistance, no pyrethroids in use.

bχ2 test (df = 1) between the two periods for each category; n.s., not significant (P > 0.05).