TABLE 1.
Effectors of copper homeostasis in E. coli and S. enterica
| Gene | Protein | Function |
|---|---|---|
| cueR | CueR | Copper-responsive transcriptional activator |
| copA | CopA | Inner membrane ATPase for efflux of cytoplasmic copper |
| copA | CopZ | Cytoplasmic chaperone |
| cueO/cuiD | CueO/CuiD | Periplasmic multicopper oxidase |
| cueP | CueP | Periplasmic binding protein |
| cusS | CusS | Copper-responsive inner membrane kinase of CusR |
| cusR | CusR | Transcriptional activator |
| cusA | CusA | Inner membrane antiporter |
| cusB | CusB | Periplasmic adapter |
| cusC | CusC | Outer membrane channel |
| cusF | CusF | Periplasmic chaperone |
| golS | GolS | Gold/copper-responsive transcriptional activator |
| golT | GolT | Inner membrane ATPase for efflux of cytoplasmic copper |
| golB | GolB | Cytoplasmic chaperone |
| cutC | MicL (sRNAa) | Post-transcriptional regulator of copper sensitivity |
a
Small non-coding regulatory RNA.